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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPE
All Species:
8.79
Human Site:
S2178
Identified Species:
16.11
UniProt:
Q02224
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02224
NP_001804.2
2701
316415
S2178
K
K
L
K
Y
V
L
S
Y
V
T
K
I
K
E
Chimpanzee
Pan troglodytes
XP_001170168
2701
316707
S2178
K
K
L
K
Y
V
L
S
Y
V
T
K
I
K
E
Rhesus Macaque
Macaca mulatta
XP_001110512
2701
316828
S2178
K
K
L
K
Y
V
L
S
Y
V
R
K
I
K
E
Dog
Lupus familis
XP_852631
1216
141588
K760
L
N
S
E
V
V
Q
K
E
S
R
I
Q
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6RT24
2474
286506
A2017
K
Y
V
L
S
S
I
A
R
I
K
E
E
Q
H
Rat
Rattus norvegicus
Q7TSP2
1385
159522
I929
K
E
N
S
S
K
E
I
L
K
A
L
E
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420670
2150
248600
I1694
S
L
H
L
N
T
Q
I
I
L
K
D
V
S
E
Frog
Xenopus laevis
NP_001080954
2954
339950
Q2375
D
E
L
R
L
Q
L
Q
C
L
E
Q
H
G
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524993
2013
231091
K1557
Q
E
L
Q
A
E
M
K
V
L
S
N
R
N
E
Honey Bee
Apis mellifera
XP_001121311
1418
164919
E962
I
L
K
N
K
V
N
E
E
L
N
S
S
E
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781622
2537
290578
N2040
V
E
L
D
S
A
R
N
L
L
S
Q
K
E
D
Poplar Tree
Populus trichocarpa
XP_002308893
1247
142380
K791
T
E
H
Q
N
F
E
K
E
E
F
L
S
Q
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187629
1348
152938
E892
R
R
D
S
L
L
V
E
R
S
A
N
Q
S
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.7
37.8
N.A.
60.5
21.2
N.A.
N.A.
37.1
31
N.A.
N.A.
26.1
24.8
N.A.
25.5
Protein Similarity:
100
99.2
98
42
N.A.
75
35.7
N.A.
N.A.
55
52.2
N.A.
N.A.
45.6
37.8
N.A.
48.8
P-Site Identity:
100
100
93.3
6.6
N.A.
6.6
6.6
N.A.
N.A.
6.6
13.3
N.A.
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
93.3
13.3
N.A.
46.6
13.3
N.A.
N.A.
20
40
N.A.
N.A.
53.3
20
N.A.
53.3
Percent
Protein Identity:
23.9
N.A.
N.A.
24.9
N.A.
N.A.
Protein Similarity:
34.6
N.A.
N.A.
37.6
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
8
0
0
16
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
8
8
0
0
0
0
0
0
0
8
0
8
8
% D
% Glu:
0
39
0
8
0
8
16
16
24
8
8
8
16
16
39
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
16
0
0
0
0
0
0
0
0
0
8
0
16
% H
% Ile:
8
0
0
0
0
0
8
16
8
8
0
8
24
0
8
% I
% Lys:
39
24
8
24
8
8
0
24
0
8
16
24
8
24
0
% K
% Leu:
8
16
47
16
16
8
31
0
16
39
0
16
0
0
16
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
8
16
0
8
8
0
0
8
16
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
16
0
8
16
8
0
0
0
16
16
16
0
% Q
% Arg:
8
8
0
8
0
0
8
0
16
0
16
0
8
0
8
% R
% Ser:
8
0
8
16
24
8
0
24
0
16
16
8
16
16
0
% S
% Thr:
8
0
0
0
0
8
0
0
0
0
16
0
0
8
0
% T
% Val:
8
0
8
0
8
39
8
0
8
24
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
24
0
0
0
24
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _